Identification and In-Silico Profiling of Phytoconstituents in Leaves of Punica grantum L.

Abstract

Punica granatum L. also called Pomegranate, a valuable fruit belonging to Punicaceae family. Pomegranate is not only nutrious but has remarkable medicinal properties. This study aimed to identify the phytochemical constituents present in Pomegranate leaves utilizing Gas Chromatography-Mass Spectrometry (GC-MS) technique, and to assess their medicinal potential using the PASS online software. The results of the analysis revealed the presence of several important phytochemicals, like Neophytadiene,Phytol,1,2 Benzene Dicarboxylic acid known for their medicinal properties such as Saccharopepsin inhibitor, Retinol dehydrogenase inhibitor, anti-inflammatory, anti-pyretic and anti-cancer. From the screened potent compounds, notably Phytol showed good activity which can be further evaluated for in-vivo drug evaluation. This study contributes to the understanding of the phytochemical composition and medicinal potential of Pomegranate leaves, highlighting its significance as a valuable natural resource for pharmaceutical research and development.