Identification and early diagnosis of choroideremia and gyrate atrophy

Abstract

Choroideremia and gyrate atrophy are two kinds of heritage primary retino-choroidal atrophy diseases. At advanced stage, their typical fundus lesions are conductive to identification. However, early diagnosis and intervention, which lead to improved prognosis and genetic benefits, are hindered by some similar clinical manifestation and optical examine results. Therefore, it is meaningful for ophthalmologists to have a comprehensive understand of these two diseases, and provide early diagnosis and proper intervention including genetic consultation.