Abstract
Background: The adrenal gland exhibits a high plasticity and chromaffin cell number can be regulated, in contrast to the closely related neurons, to meet physiological needs. It therefore has been suggested that a subpopulation of proliferation and differentiation competent progenitor cells continues to exist in the adult adrenal medulla. In our previous studies, we established protocols to in vitro enrich these cells from bovine and human adrenals in sphere cultures. These cells are characterized by the expression of neural crest and neural progenitor markers and are able to differentiate to the chromaffin and neural lineage.
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Schedule a callMore From: Experimental and Clinical Endocrinology & Diabetes
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