IDDF2021-ABS-0124 Predictors of complications and weight loss following intra gastric balloon insertion

Abstract

<h3>Background</h3> Obesity is a major global health issue and to address this, multiple weight reduction strategies are emerging. Intragastric balloon (IGB) insertion has shown to be an effective option. However, it is associated with adverse events and weight loss is variable. Hence, the aim of this study is to identify factors associated with weight loss and complications following insertion of IGB. <h3>Methods</h3> Retrospective analysis of the complications and weight loss of the patients who had IGB inserted at King Abdullah Medical City, Makkah, a tertiary referral center for Bariatric surgery. <h3>Results</h3> Of the 72 patients who had IGB inserted 24 (66.7%) developed an adverse event, including 5 early removals within 2 weeks. In multivariate stepwise backward logistic regression, female gender was identified as the only predictor of adverse event (P=0.009; odds ratio 0.247 95% confidence interval 0.086 – 0.711). The most common complication was abdominal pain occurring in 15 patients (21%). Data at 6 months follow-up was available in 67 patients with a mean percentage of excess body weight loss of 17.47%± 14.21% with a reduction of BMI of 6.33 kg/m². On a multiple regression model, weight loss at 3 months and asthma were significantly correlated with the percentage of excess weight loss (P &lt;0.001 and P = 0.04, respectively) <h3>Conclusions</h3> In this cohort, the gender of the patients was associated with complications and weight loss at 3 months and asthma predicted the final weight loss.