Abstract
Background Pancreatic exocrine and endocrine insufficiency is the common complication of chronic pancreatitis (CP). Diabetes due to diseases of the exocrine pancreas was described as pancreatogenic or pan-creatogenous diabetes mellitus (DM). Available tests to assess pancreatic exocrine function in clinical practice are not widely used. The objective of this study is to investigate the potential nutritional markers for assessment of the severity of pancreatic exocrine insufficiency in CP. Methods A retrospective analysis was performed on 158 CP patients. They were divided into two groups: CP with DM group which DM was caused by CP and receiving glucose-lowering treatment, and CP without DM group. Hemoglobin, albumin, prealbumin, calcium, phosphate, triglycerides (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), apolipoprotein A, apolipoprotein B and lipoprotein (a) were analyzed and compared between these two groups. Results Albumin, prealbumin, LDL-C were significantly lower in CP with DM group than CP without DM group (36.17±3.53 vs. 38.31±3.83, p Conclusions Serum nutritional markers are associated with pancreatic exocrine insufficiency and LDL-C may be used to evaluate the degree of pancreatic exocrine insufficiency in CP.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
