Abstract

Background This study was aimed to investigate the association between electronic cigarette (e-cig) smoking and gastroesophageal reflux disease (GERD) among the adult urban population. Methods A cross-sectional study was conducted among 267 adult people in Cirebon City, West Java, Indonesia. A self-administered questionnaire based on earlier validated GERD questionnaire (GERDQ) was given. The questionnaire consisted of demographic characteristics and the symptoms score for GERD. A symptoms score of at least 8 was considered as GERD. Data were analysed using descriptive statistics and chi-square test. Results The median age of the subjects was 24.0 years old. E-cig smoking was frequent (74.2%) among the subjects with median duration 2.0 years. The median of its dose was 30.0 ml weekly. The prevalence of GERD in this study was 9.4%. According to e-cig smoking status, the prevalence of GERD among smokers was 6.6%, while the prevalence of GERD among nonsmokers was 17.4%. The e-cig smoking was negatively associated with GERD (PR=0.334; 95% CI: 0.144–0.772; p=0.008) (table 1). Conclusions This population-based study showed that there is a statistically negative association between e-cig smoking and GERD in adult urban population. Further studies are needed to evaluate the association between e-cig smoking and GERD.

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