ID:15817 One-Year Outcomes of an SCS System Capable of Multiple Neurostimulation Modalities: A Randomized Controlled Trial

Abstract

Stimulation of different neuronal targets (e.g. Dorsal Horn, Dorsal Column) has been demonstrated in pre-clinical SCS studies to more robustly modulate neural activity and in turn, perception of pain.1,2 As such, human therapeutic neurostimulation configured in a manner to allow for stimulation of multiple simultaneous targets via the dual use of sub- and supra-perception based SCS modalities (i.e. combination therapy) may be able to enhance pain relief outcomes. In support of this postulate, positive outcomes when using combination therapy in SCS-implanted patients have now been recently reported.