ID: 3525194 ROLE OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY AND INTRADUCTAL SECRETIN TEST IN THE DIAGNOSIS OF EXOCRINE PANCREATIC INSUFFICIENCY

Abstract

Chronic Pancreatitis (CP) may be difficult to diagnose in the early stages when imaging may be normal. Exocrine pancreatic insufficiency (EPI) may be considered as a surrogate marker of CP, although not all patients with CP have EPI. During performance of endoscopic retrograde cholangiopancreatography, addition of an Intraductal Secretin Test (IDST) may further aid the evaluation of EPI, based on determination of pure pancreatic juice (PPJ) volume and bicarbonate concentration (BC). The optimal collection time for IDST is unknown.