Abstract
The strongest histologic predictor for progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) in Barrett’s esophagus (BE) is expert confirmed diagnosis of low-grade dysplasia (LGD). However, previous studies showed that up to 85% of LGD diagnosis were downstaged to non-dysplastic BE during revision. Therefore, Dutch guidelines advise to only refer patients with confirmed LGD to a Barrett’s Expert Center (BEC). Aim was to assess if a finding of confirmed LGD in BE without visible lesions (VL), diagnosed in a community setting, is an indicator for higher grades of dysplasia and if referral to a BEC is indeed necessary.
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