Abstract
PAG, or periaqueductal gray is a region of gray matter known to play a critical role in the descending pain modulation system. Despite knowledge on PAG’s role in pain modulation, little is known about its functional connectivity. This study aimed to determine how functional connectivity patterns differed in spinal cord injury (SCI) patients compared to HCs. Studying areas of functional connectivity would provide deeper anatomical and physiological understanding of PAG, as well provide information on the PAG’s role in the development and prolongation of pain in patients with chronic pain.
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