Abstract
The spinal evoked compound action potential (ECAP) is a biopotential originating from the synchronous activation of dorsal column fibers in response to spinal cord stimulation (SCS). However, the factors contributing to the unique morphology of the ECAP waveform in humans have not been well elucidated. We examine whether the ECAP morphology is related to the medial-to-lateral placement of the SCS lead. Morphometry of the spinal cord, as well as recent studies in sheep,2 indicates that the superficial dorsal columns in humans have largest fiber types located more laterally3. We hypothesize, that laterally placed contacts may be associated with shorter ECAP latency.
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