Abstract

Minimally invasive neuromodulation therapies are an advantageous low-cost, low-risk avenue to accurately deliver electrical stimulation to deep neural targets. The Injectrode, an injectable polymer composite consisting of Pt microwires, is an in-body conforming, flexible, clinical grade novel electrode platform that alleviates access to difficult-to-reach anatomical targets, such as the dorsal root ganglion (DRG). Electrical stimulation is delivered to the Injectrode via a transcutaneous electrical stimulation (TENS) patch, where it is transferred to the Injectrode via subcutaneous metal collectors. However, Injectrode stimulation via TENS depends on the geometrical configurations of the Injectrode-collector-patch system, warranting investigation into which design parameters affect neural activation in target structures.

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