Abstract
Low back pain has a prevalence of 60-70% in industrialized countries, and combined with neck pain, they made up the third costliest medical condition in 2013, at an estimated 87.6 billion dollars in medical spending.1,2 Intervertebral disc disruption accounts for greater than 42% of the back pain population, making it the most common causative etiology.3 A vital function of the intervertebral disc is to absorb shock and vibrations from activities of daily living, which preserves the spinal structure. The sponginess of the disc is attributed to proteoglycans and its’ watered structure, creating hydraulic properties within the nucleus pulposus. The disc relies on subchondral bone for nutrient and waste transfer. With aging there is desiccation and loss of mechanical integrity, leading to further degeneration of the surrounding structures.1
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
