Abstract

Headache is one of the most common neurological problems accounting for 4% of primary care consultations and up to 30% of neurology appointments. Headache disorders are a significant cause of pain and disability to individuals and are also a major societal burden. The most common treatments for chronic migraine are pharmacological and are aimed at both acute relief (e.g., nonsteroidal anti-inflammatory drugs, triptans, and ergots) and prophylaxis (e.g., propranolol, valproic acid, and topiramate). Occipital nerve stimulation (ONS) is a non-pharmacological alternative treatment for chronic migraine. Neurostimulation is thought to prevent pain by blocking signal transduction from small nociceptive fibres with non-painful signaling in larger adjacent fibres. Existing data from clinical trials support the overall safety and efficacy of occipital nerve stimulation for the treatment of chronic migraine, however, there remains little long-term data available.

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