ID: 212311 Imaging the Neural Micro-Anatomy of the Swine Spinal Cord

Abstract

The results obtained from imaging fine neural structures can potentially inform improvements in analyzing evoked compound action potentials (ECAPs) in SCS recordings. Traditional clinical imaging techniques (CT and MRI) cannot provide the high resolution which is necessary to investigate neural micro-anatomy. Histology and electron microscopy provide high resolution insights to micro-anatomy, but only with a limited field of view. In this study, we imaged stained swine cadaver spinal cord tissues with microCT to investigate the dorsal root organization, to further elucidate the anatomical substrate upon which spinal cord stimulation acts.