Abstract

Conventional spinal cord stimulation (SCS) targets the dorsal columns, an indirect target of nociceptive transmission, and utilizes large pulse amplitudes to activate more nerve fibres and produce paresthesia. This approach can provide reliable pain relief, however, there appears to be a limit to its effectiveness. An appealing, alternative target for the treatment of chronic neuropathic low back pain (CNLBP) are dorsal horn dendrites. There is evidence for their involvement in neuropathic pain and their neurophysiological response to stimulation has been documented. With this information, a novel dorsal horn activation strategy (“Subwave”) was devised consisting of a T9/10-disc bipole, 100Hz stimulation frequency, 1000μs pulse width, and amplitude set to 80% of the patient’s stimulation perception threshold or lower. The 6-month results of a clinical trial evaluating this strategy have been presented previously. The 12-month results will be presented here.

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