ID: 205775 Open-Coil Percutaneous Peripheral Nerve Stimulation Leads Facilitate Tissue Ingrowth to Enable Implantation up to 60-days

Abstract

Open-coil leads used to deliver 60-day percutaneous peripheral nerve stimulation (PNS) are designed to encourage tissue integration following percutaneous implantation, reducing “pistoning” at the skin to inhibit the ingress of contaminants and thereby reducing infection risk. A previous meta-analysis of coiled and non-coiled percutaneous leads found the infection risk of coiled leads to be approximately 25-times lower than non-coiled leads. The present study evaluated open-coil percutaneous PNS leads in a porcine model over the course of a 60-day implant period to assess the timeline and extent of tissue ingrowth.