Abstract
Painful diabetic peripheral neuropathy (PDPN) is defined as ‘pain caused by lesions of the somatosensory system, attributed to diabetes’, and is reported to develop in 10-20% of patients suffering from diabetes mellitus. Conservative pharmacological treatment alone often offers little pain relief and is frequently poorly tolerated. Therefore, better treatment options are a necessity. The first use of spinal cord stimulation (SCS) for PDPN dates from 1996. High-quality studies followed, showing SCS to be up to 8 times more effective in terms of pain relief than best medical treatment at that time. Because most studies only evaluated short-term efficacy of SCS, long-term efficacy remains yet unclear. The aim of this study is to evaluate the long-term effects of spinal cord stimulation (SCS) in patients with painful diabetic polyneuropathy (PDPN).
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