Abstract

The amygdala is known to be an important component of the epileptic network in patients with mesial temporal lobe epilepsy (mTLE). Using single-pulse electrical stimulation (SPES), the reciprocal functional connectivity (i.e., outward connectivity vs. inward connectivity) of the amygdala to the hippocampus has been well characterized.1 However, to our knowledge, the frequency-specific and time-varying components of amygdala reciprocal connectivity to the rest of the brain has not been well characterized with SPES.

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