Abstract
The family Nodaviridae includes two genera, Alphanodavirus and Betanodavirus. The family name derives from the Japanese village of Nodamura where Nodamura virus was first isolated from Culex tritaeniorhynchus mosquitoes. Virions are non-enveloped and spherical in shape with icosahedral symmetry (T=3) and diameters ranging from 25 to 33 nm. The genome consists of two molecules of single-stranded positive-sense RNA: RNA1 and RNA2. The virion capsid consists of 180 protein subunits arranged on a T=3 surface lattice. Alphanodaviruses infect insects, whereas betanodaviruses are pathogens of fish. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Nodaviridae, which is available at www.ictv.global/report/nodaviridae.
Highlights
The family Nodaviridae includes two genera, Alphanodavirus and Betanodavirus
Electron microscopy of negatively stained betanodaviruses shows surface projections; these are not observed in alphanodaviruses
The genome of nodaviruses consists of two molecules of positive-sense single-stranded RNA; RNA of 3.1 kb (RNA1) (3.1 kb) encoding protein A, an RNA-dependent RNA polymerase of about 112 kDa (983–1014 amino acids), and RNA2 (1.4 kb) encoding protein a, the capsid protein precursor
Summary
The family Nodaviridae includes two genera, Alphanodavirus and Betanodavirus. The family name derives from the Japanese village of Nodamura where Nodamura virus was first isolated from Culex tritaeniorhynchus mosquitoes. Typical member: Striped jack nervous necrosis virus (RNA1: AB056571; RNA2: AB056572), species Striped jack nervous necrosis virus, genus Betanodavirus Virion Genome Replication Translation Host range Taxonomy
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