Abstract
Ten venoms from marine cone snails were tested for ichthyotoxic effects on zebra fish ( Brachydanio rerio) when added to the water. Only two venoms, from Conus capitaneus and Conus episcopatus, produced lethal effects at high concentrations (50–300 μg/ml) within 20–90 min. No sedative or hypnotic symptoms were observed. The experiments confirm that Conus venoms exert a quick and prompt activity only by parenteral injection into the prey as it is performed by the snail.
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