Abstract

Acquired ichthyosis is a known paraneoplastic sign of lymphoproliferative malignancies, with histopathologic findings that are nonspecific, revealing no insinuation of the underlying neoplasm. Mycosis fungoides (MF) is a skin malignancy of T helper lymphocytes with a wide clinical spectrum. Among the atypical variants of MF, there is an ichthyosis- like presentation. However, to date, rare cases of ichthyosiform MF has been reported. We report here the clinical and histopathological features of patient with IMF.

Highlights

  • Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma (CTCL) and is characterized by the clonal expansion of skinhoming T lymphocytes

  • We report here the clinical and histopathological features of patient with Ichthyosiform MF (IMF)

  • A 56-year-old man had consulted for ichthyosiform eruption of the lower extremities evolving for 2 years associated with maculopapules discreetly pruritic trunk of more recent appearance and polyadenopathy

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Summary

Introduction

Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma (CTCL) and is characterized by the clonal expansion of skinhoming T lymphocytes. Various clinical and histological variants of MF have been reported. Ichthyosiform MF (IMF) is not as well-known as other variants of MF. We report here the clinical and histopathological features of patient with IMF

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