Abstract
IntroductionVitamin D is increasingly recognized to have several beneficial effects. Vitamin D deficiency is widely prevalent. Physicians often treat patients with high doses of vitamin D for various ailments without any monitoring for adverse effects and the prescribed doses often far exceed requirements resulting in toxicity. We present here a classic case of iatrogenic hypervitaminosis D, which presented with persistent vomiting and acute renal failure.Case presentationHere we present a case of a 45-year-old Asian Indian woman who presented to us with persistent vomiting the cause of which was iatrogenic hypervitaminosis D. She was treated with intravenous fluid, diuretics and calcitonin and had clinical improvement.ConclusionsWe suggest that in any patient presenting with persistent vomiting and hypercalcemia, particularly in the presence of normal parathyroid hormone, a diagnosis of overdose of vitamin D should be suspected. Its treatment not only alleviates symptoms but also prevents ongoing acute kidney injury.
Highlights
Vitamin D is increasingly recognized to have several beneficial effects
Case presentation: Here we present a case of a 45-year-old Asian Indian woman who presented to us with persistent vomiting the cause of which was iatrogenic hypervitaminosis D
We suggest that in any patient presenting with persistent vomiting and hypercalcemia, in the presence of normal parathyroid hormone, a diagnosis of overdose of vitamin D should be suspected
Summary
We conclude that if a patient presents with persistent vomiting and hypercalcemia in the presence of normal parathyroid hormone, a diagnosis of overdose of vitamin D should be suspected because its correction alleviates symptoms but can prevent acute kidney injury. Consent Written informed consent was obtained from the patient for publication of this manuscript and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Competing interests The authors declare that they have no competing interests. Authors’ contributions RKB was the resident in charge of the case and was a major contributor in writing the initial draft of the manuscript. PT, PS, VS, NB, VA and AK contributed in writing and editing the manuscript. NB was the attending physician in charge of the case and was responsible for sections on the diagnosis and management of the patient. AA was the unit head and was responsible for management of the patient and supervised and edited the case report. All authors read and approved the final manuscript
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