I2‐Mediated Oxidation of Amines in Water toward Imines and Amides

Abstract

AbstractA sustainable oxidation reaction of amines in water is established for the synthesis of imines and amides employing environmentally benign molecular iodine as the sole oxidant. The features of the present reaction also include no use of transition metals, operational simplicity and gram‐scale synthesis. It provides a facile access to imine and amide derivatives including bioactive molecules from readily accessible amine precursors.