I.接近足月早產兒於出生18個月時降低母親健康相關生活品質:一個以台灣人口為基礎的世代研究II.接近足月早產兒母親健康相關生活品質的縱向變化

Abstract

I. Objective: To determine the health-related quality of life (HRQOL) in parents after the birth of a late preterm infant at 18 months. Methods: Mother and child were chosen via a stratified sampling from Taiwan national birth registration database in 2005.Subjects underwent a home interview 18 months after their deliveries between Jan 2007 and Feb 2008.We used the Medical Outcomes Study 36-itemShort-Form (SF-36) to measure the HRQOL of 14,578 parents of 813 late preterm infants versus 13,765 term infants. Results: The mothers with late preterm infants lowered on score of HRQOL compared to those with full-term infants. After controlling for potential confounding factors, of the eight domains score of the SF-36, the four domains including role limitations due to physical health, general health perception, energy vitality and mental health, the HRQOL were significantly different between these two groups of mothers (P < 0.05). Interestingly, no significant decreasing scores of the HRQOL were noted between the father with a late preterm infant and those with a term infant. Conclusion: In our knowledge, this is the first study to primarily explore the difference in the HRQOL among the parents with LPIs and the parents with term infants. In our study, being a mother of LPIs decreased the health-related quality of life included physical and mental domains as compared to those of full-term infants at 18 months of age. II. Objective: To determine the change of health-related quality of life (HRQOL) experienced over time by mother with late preterm infants (LPIs). Methods: The mother and infant were chosen via a stratified sampling from Taiwan national birth registration database in 2005. Longitudinal prospective follow-up study of mothers with late preterm infants and infants from birth to 3 years was performed. We used the Medical Outcomes Study 36-itemShort-Form (SF-36) to measure the health-related quality of life by 13,077 parents of 730 late preterm infants versus 12,347 term infants. Results: There was negative association with LPIs and maternal quality of life at 6 months and 18 months after birth. The differences among three out of the eight domains at 6 months were statistically significant (P<0.05) including physical functioning, role limitation due to Emotional problems and mental health. The differences among two out of the eight domains at 18 months were statistically significant (P<0.05) including general health perception and mental health. The difference with regards to maternal quality of life between LPIs and full-term infant was disappeared at 36 months after birth. Conclusion: In our knowledge, this is the first study to primarily explore the longitudinal change in the HRQOL experienced over time by mother with LPIs. In our study, being a mother of LPIs decreased the health-related quality of life included physical and mental domains as compared to those of full-term infants at 6 and 18 months of age.