I. New developments in instrumentation. Introductory remarks

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The purposes we envisaged that this meeting might serve was to provide, especially for biologists, a review of the current position in electron microscopy and an estimate of what further developments are likely or feasible in the fairly near future. We are very fortunate that so many distinguished workers in this field have been able to come to the meeting, so that they can, in section I, describe the capabilities of the most advanced forms of electron microscope at present available, and the additional devices and techniques that can be used to improve the quality of the information that the instrument gives us about a specimen. Then, in section II, we will hear about various advances in specimen preparation techniques, especially ones depending on physical approaches to the problem and, in section III, about various ways of handling and manipulating the information recorded in the electron micrographs themselves so that we can extract from them the maximum amount of reliable information about the three-dimensional structures which are being examined.