Abstract

Most Malawian women who start ART under Option B+ are still in care three years later, a higher than average adherence rate for life-threatening chronic disease treatments, worldwide (50%). We asked 75 Malawian on ART their motivations for remaining in treatment, and what barriers they overcame. Focus groups and interviews included 75 women on ART for 6+ months, at 12 health facilities. Four main motivations for continuing ART emerged: 1) evidence that ART improved their own and their children’s health; 2) strong desire to be healthy and keep their children healthy; 3) treatment was socially supported; 4) HIV/ART counselling effectively showed benefits of ART and told women what to expect. Women surmounted the following barriers: 1) stigma; 2) health care system; 3) economic; 4) side effects. Women stayed on ART because they believed it works. Future interventions should focus on emphasizing ART’s effectiveness, along with other services they provide.

Highlights

  • In 2011, Malawi implemented an innovative policy (“Option B+”) to prevent mother-to-child transmission (PMTCT) by providing lifelong antiretroviral therapy (ART) to all HIV-infected pregnant and breastfeeding women [1, 2]

  • We recently reported that 70% of the 29,313 women who started ART under Option B+ in Malawi by June 2012 were still in care three years later [5] and about 70% of the retained women adequately adhered during the first 2 years of ART [6]

  • We interviewed women and conducted focus group discussions (FGDs) until we reached data saturation

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Summary

Introduction

In 2011, Malawi implemented an innovative policy (“Option B+”) to prevent mother-to-child transmission (PMTCT) by providing lifelong ART to all HIV-infected pregnant and breastfeeding women [1, 2]. Option B+ was subsequently adopted by other countries and is recommended by WHO [3]. In Option B+ treatment programs, poor adherence, retention and loss-to-follow-up (LTFU) are still serious concerns, and continuation on long-term therapy is a critical element of HIV care [4]. We recently reported that 70% of the 29,313 women who started ART under Option B+ in Malawi by June 2012 were still in care three years later [5] and about 70% of the retained women adequately adhered during the first 2 years of ART [6]. If we take a global perspective on long-term therapy for chronic life-threatening diseases, Malawi’s Option B+ adherence and retention rates are impressively high, and much higher than in some other countries that have adopted the program. If we take a global perspective on long-term therapy for chronic life-threatening diseases, Malawi’s Option B+ adherence and retention rates are impressively high, and much higher than in some other countries that have adopted the program. [7] Most papers on the Malawi Option B+ program examine retention and adherence, but do not put their findings into

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