Abstract

Decision making in the face of conflicting ethical demands has intrigued mankind for millennia. A long philosophical tradition has placed emphasis on reasoning, about utilitarian outcomes, for example, in such decisions (1). However, recent work in social neuroscience (2, 3) has identified brain circuits active during moral judgment that have been linked to prosocial emotions such as empathy, guilt, and pity. Using an innovative combination of behavioral research and pharmacological intervention, a study in this issue of PNAS (4) suggests a role for the neurotransmitter serotonin in the neural substrate of ethical decision making.

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