Abstract

The level of micronuclei and other nuclear anomalies in the exfoliative cells of the oral mucosa of diabetes mellitus type I patients and healthy subjects was investigated using the micronucleus test. Correlation analysis was performed based on the results obtained in the exfoliative cells of patients with type I diabetes of the Armenian population with the micronucleus test, their laboratory and anthropometric data, and an extremely small p-value was obtained, which shows very strong evidence of the obtained correlational relationship. Therefore, the research conducted allows us to conclude that type I diabetes has a statistically significant effect on the genetic instability of the organism of patients with diabetes, at the same time having a statistically high cytotoxic and genotoxic effect.

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