HYSTEROSCOPIC CORRECTION OF INTRACAVITARY LESIONS DOES NOT AFFECT THE ENDOMETRIAL VOLUME AND SUBENDOMETRIAL VASCULARITY BEFORE ICSI

Abstract

To evaluate the endometrial volume and subendometrial blood flow measured by three-dimensional power Doppler (3DPD) at the day of ovum pick-up after hysteroscopic correction of intracavitary lesions. A prospective cohort study enrolled 106 women undergoing their first ICSI cycles. All women had a history of previous hysteroscopic surgery for correction of intracavitary lesions within six months before ICSI trial. Fifty-five (51.9%) women had a history of polypectomy; 29 (27.4%) metroplasty, 12 (11.3%) adhesiolysis and ten (9.4%) had a history of myomectomy. A control group of 122 women with normal uterine cavity diagnosed by office hysteroscopy were included. On the day of ovum pick-up; endometrial volume and subendometrial blood flow was assessed using 3DPD, and vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated and compared between both groups. Additionally, pulsatility index (PI) and resistance index (RI) of uterine vessels were assessed. The endometrial volume was comparable between both groups (4.28 ± 1.62 vs. 4.78 ± 1.44, p=0.055). Additionally, no significant differences in subendometrial VI, FI and VFI between both groups (p= 0.44, 0.13, 0.717 respectively). Finally, the uterine PI and RI were comparable between both groups (0.83 ± 0.06 vs. 0.84 ± 0.05 and 2.39 ± 0.57 vs. 2.38 ± 0.50, p= 0.981 and 0.577 respectively) Hysteroscopic correction of intracavitary lesions does not affect the endometrial volume and subendometrial vascularity before ICSI cycles