Abstract
We have investigated, in volunteers, the effect of inhaling 50% nitrous oxide in oxygen on subsequent oxygenation. Subjects breathed either 50% nitrous oxide in oxygen or 50% nitrogen in oxygen during hyperventilation and normal ventilation. Arterial oxygen saturation and end-expired oxygen concentrations were lower after 50% nitrous oxide in oxygen than after the other mixture with both patterns of ventilation and were lowest after hyperventilation with 50% nitrous oxide in oxygen.
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