Abstract
The effects of thyroid hormones on the kidneys are well known. Thyroid dysfunction causes remarkable changes in glomerular and tubular functions and electrolyte and water homeostasis. There have been reports of elevated serum creatinine associated with hypothyroidism, the pathogenesis of which is thought to be multi-factorial. We present five cases, all of who were referred to the nephrology department for evaluation of unexplained „acute kidney injury‟. Hypothyroidism was suspected based on history and clinical examination. In all cases, investigation revealed significantly elevated TSH, low T3, T4 levels, elevated CPK levels, normal urine analysis and normal sonological study of kidney. All the cases showed complete normalization of renal parameters after 4-8 weeks of treatment with levothyroxine. This case series depicts the need for high index of suspicion for diagnosis of hypothyroidism in the setting of unexplained „acute kidney injury‟.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
