Abstract
Hypothesizing High Negative Emotionality as a Function of Genetic Addiction Risk Severity (GARS) Testing in Alcohol Use Disorder (AUD).
Highlights
While there are several effective treatment options for alcohol use disorder (AUD), attrition, and relapse are common in AUD treatment, especially in terms of the numbers of DWI arrests [2]
It is well-known that 1035% of subjects drop out from AUD clinical trials, and more than 60% relapse in the year following treatment [3]
It is known that AUD-type patients with negative emotionality have a higher likelihood of benefitting from favorable outcomes following mindfulness-based relapse prevention [5]
Summary
While there are several effective treatment options for AUD, attrition, and relapse are common in AUD treatment, especially in terms of the numbers of DWI arrests [2]. While precision medicine including genetic antecedents may provide important information that could help identify specific DNA variants in the Brain Reward Circuitry, it is important to identify negative emotionality, especially in repeat DWI offenders [4].
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