Abstract
This hypothesis is that anorexia nervosa (AN) is a biologically driven disorder, and mammalian hibernation may offer clues to its pathogenesis. Using this approach, this hypothesis offers suggestions for employing heart rate variability as an early diagnostic test for AN; employing the ketogenic diet for refeeding patients, attending to omega 3:6 ratio of polyunsaturated fatty acids (PUFAs) in the refeeding diet; and exploring clinical trials of the endocannabinoid-like agent, palmitoylethanolamde for patients with AN. This hypothesis also explores the role of lipids and autoimmune phenomena in AN, and suggest a lipodomics study to search for antibodies in the serum on patients with AN.
Highlights
Barbara Scolnick*Specialty section: This article was submitted to Eating Behavior, a section of the journal Frontiers in Psychology
Anorexia nervosa (AN) is a severe disorder characterized by self-starvation, hyperactivity, and distorted body image (Kaye et al, 2009; American Psychiatric Association, 2013)
Oftentimes one article would lead to many more. Some topics, such as heart rate variability in anorexia nervosa (AN), ketogenic diet in AN, or endocannabinoid changes in patients with AN had less than 20 articles, all papers referenced in Public Med were reviewed, and all the relevant articles are referenced in the text
Summary
Specialty section: This article was submitted to Eating Behavior, a section of the journal Frontiers in Psychology
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