Abstract
The seasonality of births of persons who later develop schizophrenia is one of the most firmly established facts about this disease. At least 44 studies in 18 different countries including Italy have confirmed that an, excess number of schizophrenics are born in the winter and spring months [1–4]. According to one recent review “in studies with a sample size of over 1,500 the excess ranges from 0 to 20 percent with a mean of about 10 percent” [3]. The trend is more clearly evident in studies of northern hemisphere countries, but the trend in southern hemisphere countries is in the same direction corresponding with their reversed seasons. It is also now widely accepted that the seasonal excess of schizophrenic births is real and not a statistical artifact based on age-incidence or age-prevalence effects [3].
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