Hypothalamo-amygdala-prefrontal network in reward seeking

Abstract

Event Abstract Back to Event Hypothalamo-amygdala-prefrontal network in reward seeking Shuji Aou1*, Kimiya Narikiyo1, Akira Masuda1, Noboru Shiota1 and Takao Inoue1 1 Kyushu Institute of Technology, Department of Brain Science and Engineering, Japan Foods, sexual/social partners, family and friends are essential natural rewards for humans and animals. We are trying to make great efforts to get these rewards, however, the numbers of patients who failed to manipulate these rewards, such as eating disorders, reproductive dysfunctions, emotional disorders, various types of addiction and social dysfunctions including autism and other communication problems are greatly increasing in modern societies under the influences of drastic changes in environments and social systems. It has been studied that the hypothalamo- amygdala-prefrontal network is deeply involved in neural control of reward-seeking behaviors. Hypothalamic neurons show specific responses to different natural rewards. The amygdala plays an important roles in emotional evaluation of rewards and punishments. The orbitofrontal cortex (OFC) has been shown to evaluate reward value based on integration of multimodal sensory inputs and endogenous humoral signals. OFC neurons showed selective responses to each category of rewards. Animal behaviors are highly sensitive to environmental chemicals especially during developing period. Certain artificial chemicals such as environmental endocrine disrupters have aversive effects on normal development of behaviors including reward-seeking behavior through affecting hypothaloamo-amygdala-prefrontal network. In contrast, natural environmental chemicals such as plant-derived odors have beneficial effects on our various behaviors. Dynamic properties of hypothalamo-amygdala-prefrontal network in reward seeking under the influence of chemical environments will be discussed. Conference: IBRO International Workshop 2010, Pécs, Hungary, 21 Jan - 23 Jan, 2010. Presentation Type: Oral Presentation Topic: Abstracts Citation: Aou S, Narikiyo K, Masuda A, Shiota N and Inoue T (2010). Hypothalamo-amygdala-prefrontal network in reward seeking. Front. Neurosci. Conference Abstract: IBRO International Workshop 2010. doi: 10.3389/conf.fnins.2010.10.00222 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 04 May 2010; Published Online: 04 May 2010. * Correspondence: Shuji Aou, Kyushu Institute of Technology, Department of Brain Science and Engineering, Kitakyushu, Japan, aou@brain.kyutech.ac.jp Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Shuji Aou Kimiya Narikiyo Akira Masuda Noboru Shiota Takao Inoue Google Shuji Aou Kimiya Narikiyo Akira Masuda Noboru Shiota Takao Inoue Google Scholar Shuji Aou Kimiya Narikiyo Akira Masuda Noboru Shiota Takao Inoue PubMed Shuji Aou Kimiya Narikiyo Akira Masuda Noboru Shiota Takao Inoue Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.