Abstract
The study objective is to analyze scientific literature on hypothalamic hamartomas’ diagnostics and treatment. Materials and methods. We studied 90 scientific sources, published between 1948 and 2019. Results. The paper describes clinical picture of hypothalamic hamartomas, their various classifications, specificity of neuroimaging and neurophysiological diagnostics and pathomorphological research, the surgical treatment. Conclusion. Transnasal resection is a promising and noninvasive method to treat hypothalamic hamartomas of IV and V types by J. Régis classification. According to the scientific literature, stereotactic destruction can be used to resect hamartomas of I–IV types; types II and III require endoscopic transventricular approach, while types IV and V can be resected using endoscopic transnasal transsphenoidal approach.
Highlights
Цель исследования – провести анализ научной литературы, посвященной вопросам диагностики и лечения гипоталамических гамартом
We studied 90 scientific sources, published between 1948 and 2019
С. Трифонов: обзор публикаций по теме статьи, написание текста статьи
Summary
Цель исследования – провести анализ научной литературы, посвященной вопросам диагностики и лечения гипоталамических гамартом. Для удаления I–IV типов гамартом могут быть применены стереотаксические методы деструкции, для II и III типов методом выбора считается эндоскопический трансвентрикулярный доступ, а при IV и V типах может быть выполнено трансназальное транссфеноидальное эндоскопическое удаление. The study objective is to analyze scientific literature on hypothalamic hamartomas’ diagnostics and treatment. The paper describes clinical picture of hypothalamic hamartomas, their various classifications, specificity of neuroimaging and neurophysiological diagnostics and pathomorphological research, the surgical treatment. Transnasal resection is a promising and noninvasive method to treat hypothalamic hamartomas of IV and V types by J. According to the scientific literature, stereotactic destruction can be used to resect hamartomas of I–IV types; types II and III require endoscopic transventricular approach, while types IV and V can be resected using endoscopic transnasal transsphenoidal approach. Yu., Sinkin М.V., Grigorieva Е.V., Trifonov I.S. Hypothalamic hamartoma.
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