Abstract

1. 1. Ragweed-sensitive patients who had never received previous hyposensitization therapy were divided randomly into 3 groups. Either repository, placebo, or aqueous therapy was administered to each group. Following aqueous therapy, 16 of 21 patients responded satisfactorily. In both the repository and placebo groups, 11 of 19 patients had a satisfactory clinical response. The study was conducted in a double-blind manner. 2. 2. There was no correlation between the clinical response and the change in hemagglutination titer. 3. 3. There was a slight suggestion that patients with an elevated reagin titer or a rising reagin titer have a poorer therapeutic response to specific therapy.

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