Abstract
The intracerebroventricular administration of ACTH 1–24 (3–5 μg/rat) produced a behavioural syndrome characterized by recurrent episodes of penile erection and yawning in rats. Hypophysectomy prevented ACTH 1–24-induced yawning and penile erection. These results suggest that pituitary has a “trophic” action not only on peripheral target organs but also on structures in brain controlling specific behavioural responses.
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