Hypophosphatemia in Recurrent Renal Stone Formers — Consequence of Arterial Hypertension?

Abstract

Fasting hypophosphatemia is commonly found in recurrent renal stone formers (calcium oxalate and/or -phosphate) with absorptive hypercalciurial1,2. However, not all authors were able to demonstrate lower plasma phosphorus levels in recurrent renal stone formers as compared with matched control individuals3,4. Hypophosphatemia is of interest in view of some recent proposals which try to link plasma phosphate and intestinal hyperabsorption of calcium in the pathogenesis of the hypercalciuria of recurrent renal stone formers via increased circulating levels of 1,25(OH)2 vitamin D5.