Abstract
Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease.
Highlights
Alzheimer disease (AD) and cerebrovascular accidents (CVA) are the two leading causes of age-related dementia
Recent advances on several fronts suggest that the vascular risk factors, which are linked to cerebrovascular disease and stroke in the elderly, significantly increase the risk of AD
Irrespective of the ultimate pathogenic mechanism, these findings suggest that managing vascular disease is important in the treatment and prevention of AD or mixed dementia
Summary
Alzheimer disease (AD) and cerebrovascular accidents (CVA) are the two leading causes of age-related dementia. Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease Recent advances on several fronts suggest that the vascular risk factors, which are linked to cerebrovascular disease and stroke in the elderly, significantly increase the risk of AD.
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