Hyponatremia in Infants with cystic fibrosis

Abstract

Hyponatremia can be a presenting symptom of cystic fibrosis in infancy, especially in countries with hot climates. In this issue of The Journal, Guimarães et al from the Universidade Federal de Minas Gerais, Brazil, have evaluated hyponatremia at diagnosis and then longitudinally in 20 infants with cystic fibrosis. They demonstrated that 95% of the patients had hyponatremia at the time of diagnosis, and the serum sodium levels had normalized within the first year. Factors associated with variations in serum sodium were diet and ambient temperature. Their findings indicate that infants with cystic fibrosis in hot countries are still at risk for developing hyponatremia even when receiving an increased salt intake. Article page 285▶ Prevalence of Hyponatremia at Diagnosis and Factors Associated with the Longitudinal Variation in Serum Sodium Levels in Infants with Cystic FibrosisThe Journal of PediatricsVol. 161Issue 2PreviewTo determine the prevalence of hyponatremia at diagnosis in patients with cystic fibrosis and identify the factors associated with changes in serum sodium concentration over time. Full-Text PDF