Abstract

In recent years in Ukraine and in the world there has been a clear tendency towards deterioration in the indicators of the somatic health of children and adolescents, that is negatively affects the processes of reproductive health formation and it state in the future. Concern for adolescent girl's health, including their reproductive system, forms an enormous contribution to the society future. That's why big attention is paid to the formation and saving reproductive health of adolescent girls. The period of sexual development is defining in a woman's life and is considered a key moment on the path of reproductive maturity. Today it has been established that the reproductive health formation is influenced by environmental, socio-economic factors and the presence of somatic diseases. Despite the fact that the pathogenetic mechanisms of the reproductive system formation are extremely complex and sensitive to the effects of negative factors, the appearance of destructive factors at this time can disrupt the physiological chain of functioning of the hormonal mechanisms which regulate the reproductive system. Disorders of the menstrual cycle is one of the most common pathological conditions, combining pathogenetically different diseases, which are manifested by a violation of the menstrual duration and frequency, amount of menstrual flow. According to domestic literature, hypomenstrual syndrome (oligomenorrhea, amenorrhea) is in the first place among menstrual dysfunctions in adolescent girls in the structure of gynecological morbidity and is up to 45%. Menstrual irregularities that occur during adolescence often persist into the future, causing infertility, obstetric pathology, perinatal loss and other reproductive health problems during childbearing years. The problem of the menstrual cycle formation has been little studied, but it is socially significant, very relevant and requires further study.Thus, girls with menstrual disorders constitute a group of increased risk of gynecological diseases in women of reproductive age, since many chronic diseases of adults are a protracted pathology of adolescents. Therefore, adolescent girls should be examined and treated by a specialist in pediatric and adolescent gynecology, pediatric endocrinologist, pediatrician and family doctor.

Highlights

  • The nation's reproductive health problems are closely related to the effective health improvement of adolescent girls, which is one of the priority areas of modern medical science [4, 11, 27]

  • Menstrual dysfunctions that occurred of adolescence account for 20% in the structure of gynecological diseases in adolescent girls and often persist in the future, causing infertility, obstetric pathology, perinatal losses, and other reproductive health disorders in childbearing age [12, 21, 24, 32, 38, 40]

  • Girls with menstrual dysfunctions form a high-risk group for the occurrence of gynecological diseases in women of reproductive age, since many chronic diseases of adults are a prolonged pathology of adolescents [32]

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Summary

LITERATURE REVIEW

V.V. ARTYOMENKO MD, PhD, DSc(Med), professor, Department of Obstetrics and Gynecology, Odesa National Medical University, Odesa ORCID: 0000-0003-2490-375X. N.M. NASTRADINA PhD, associate professor, Department of Obstetrics and Gynecology, Odesa National Medical University, Odesa ORCID: 0000-0001-8688-2259. K.O. NITOCHKO PhD, associate professor, Department of Obstetrics and Gynecology, Odesa National Medical University, Odesa ORCID: 0000-0002-3750-0098. M.A. ALTYIEVA clinical resident, Department of Obstetrics and Gynecology, Odesa National Medical University, Odesa ORCID: 0000-0002-8839-3202

INTRODUCTION
CONCLUSIONS
Роль мелатонина и ингибина В в патогенезе олигоменореи
Особливості перебігу пубертатного періоду у дівчат із
Findings
International Statistical Classification of Diseases and Related Health
Full Text
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