HYPOLIPIDMIC EFFECT OF JAMUN SYZYGIUM CUMINI

Abstract

The present work aims to study the potential effect of jamun Syzygium cumini seeds and leaves to give more protection against hyperlipidemia . Twenty male albino rats were used over 30 days period. The animals were divided into (4) groups, wherein groups number (1) represent control which were fed basal diet, while group number (2) was received high fat diet to serve as hyperlipidemic group. Other two groups allowed to feed high fat diet supplemented with jamun seeds and leaves, group number (3) treated simultaneously with jamun seeds, fourth group treated with jamun leaves. At the end of the experimental period, blood samples were collected to determine lipid profile, liver functions and determine the kidney functions include urea nitrogen and creatinine. From the obtained results we concluded that group of rats fed on high fat diet were considered as a major risk factor for hyperlipidemia disease. Our results could be summarized that jamun seeds and jamun leaves were considered the best for causing a reduction of TC, TG and LDL. Also, liver functions has been improved and there were significant reduction GOT, GPT and ALP activity than that of positive control group. It could be concluded that jamun seeds and jamun leaves under study are useful for the treatment of hyperlipidemia.