Abstract
Milk is a rich and complete nutritive food provided by nature. The present study, reports the hypolipidemic and antioxidant effects of camel milk supplementation in the management of hyperlipidemia associated with obesity. Rats were rendered obese by feeding them with a high-fat diet for eight weeks to induce hyperlipidemia. The supplementation of camel milk as shown by atherogenic index, and a battery of biochemical markers of oxidative stress, lipid profile, antioxidant vitamins, markedly improved and ameliorated hyperlipidemia in rats. It also significantly (p<0.05) lowered the elevated levels of aspartate aminotransferase, alanine aminotransferase, creatinine, and urea. The data provided evidence supporting the beneficial effect of camel milk on hyperlipidemia associated with obesity. The study assumes significance because of the fact that hyperlipidemia is associated with metabolic syndrome that leads to the development of chronic inflammatory diseases such as diabetes and atherosclerosis.
 Keywords: Antioxidant; hypolipidemia; Camel milk; Obesity; High-Fat Diet; chronic inflammatory diseases
Highlights
Hyperlipidemia is considered as the fifth leading cause of death in the world[1]
The study assumes significance because of the fact that hyperlipidemia is associated with metabolic syndrome that leads to the development of chronic inflammatory diseases such as diabetes and atherosclerosis
A significant decrease (p
Summary
Hyperlipidemia is considered as the fifth leading cause of death in the world[1]. Hyperlipidemia is caused by ingestion of largely fat containing diet of mostly animal origin in excess amount. Uncontrolled diet and sedentarylifestyle (physical inactivity) are some of the factors that are directly linked with overweight, obesity, metabolic syndrome, diabetes and atherosclerosis. They are seen as metabolic disorders associated with lipid metabolism. Metabolic disorders of lipid metabolism are characterized by high levels of lipids circulating in the blood[1]. When the circulating lipids in the body rise, it leads to thedevelopment of a number of life threatening devastating chronic metabolic complications such as atherosclerosis, diabetes and cardiovascular diseases[2]
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