Abstract
Previous epidemiological studies and animal experiments in rodents have demonstrated that drinking green tea is associated with decreased levels of serum total cholesterol (TC) and triacylglycerols (TG). However, the mechanisms involved remain poorly understood. We have studied the hypolipidemic activity of jasmine green tea epicatechins (GTE) and tested the various mechanisms which might be responsible for this lipid-lowering effect using hamsters as an animal model. The results showed that GTE either added in diet or in drinking water lowered significantly the levels of TC and TG in both serum and liver. GTE had no effect on the activity of liver fatty acid synthase, 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase and intestinal acyl CoA:cholesterol acyltransferase (ACAT). However, GTE increased significantly the fecal excretion of total fatty acids, neutral and acidic sterols. It is most likely that the hypolipidemic activity of GTE is mediated by its inhibition of absorption of cholesterol and TG.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
