Abstract
Hypoglycemic effects was observed with Spirulina (Spirulinaplatensis) when given as leaf extract in normal and alloxan diabetic rat. In this study 150 rats were included and divided into three groups of ten rats in each group. First group was normal control (A), Second group was diabetic control (B), third group was diabetic with Spirulina treated (C). The rats were treated with aqueous extract of Spirulina at a dose rate of 20 mg/kg body weight respectively for 3 weeks. During experimental period, day 0, day 7, day 14 and day 21 blood samples were collected from all groups and determined their blood sugar level using diabetic kit. The blood glucose levels were reduced from 165.5±10.65 mg/dL to 158.17±5.49 mg/dL in group C after 3 weeks treatment. On the other hand the average body weight were increased from 255.67±7.35 g to 286.17±8.56 g in group C after 3 weeks treatment. From the findings it is concluded that the Spirulina can be used as anti-diabetogenic agent in food.
 Res. Agric., Livest. Fish.7(3): 475-479, December 2020
Highlights
Diabetes is one of the major degenerative diseases in the world today
Diabetes mellitus (DM) is characterized by elevated plasma glucose concentrations resulting from insufficient insulin, insulin resistance or both leading to metabolic abnormalities in carbohydrates, lipids and proteins (Bos and Agyemang, 2013; Pankaj and Varma, 2013)
The study was carried out to evaluate the effects of Spirulina on blood glucose and body weight
Summary
Diabetes is one of the major degenerative diseases in the world today. It is considered as one of the five leading causes of death in the world. Diabetes mellitus (DM) is characterized by elevated plasma glucose concentrations resulting from insufficient insulin, insulin resistance or both leading to metabolic abnormalities in carbohydrates, lipids and proteins (Bos and Agyemang, 2013; Pankaj and Varma, 2013). It is a major risk factor for the development of cardiovascular disease. Modern synthetic antidiabetic drugs have series of drawbacks including their adverse effects and high cost involvement (Abdel-Daim and Halawa, 2014). Complementary and alternative medicine involves the use of medicinal plant alternatives to mainstream treatment
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