Abstract
Diabetes mellitus is an important metabolic disorder and owing to its significant health impacts is a leading cause of death around the globe. According to WHO estimates, Pakistan is the 7th highest diabetes affected population of the world where almost 7 million peoples are suffering from the disease. Flaxseed lignan and beta glucan have constructive role in controlling diabetes. In connection to their enhanced insulin sensitivity, dietary supplementation of flaxseed fiber has shown potential results in postmenopausal diabetic women. The subject population was feed with lignan and beta glucan capsules and hypoglycemic activity was monitored both on daily and weekly basis. Blood samples was taken to observe the blood glucose by use of flaxseed lignan and β glucan in postmenopausal women. Fasting and random glucose levels of postmenopausal diabetic women in 4 weeks fed on flaxseed lignan and β glucan (P<0.01). Liver and kidney functioning tests are found to be non-significant. This research indicates that flaxseed lignan and β glucan reduces the random and fasting blood glucose levels in postmenopausal patients.
Highlights
Diabetes mellitus is an endocrine disorder described by hyperglycemia and inadequate discharge of endogenous insulin
The current research was conducted with objective to assess the hypoglycemic effect of flaxseed lignan and β glucan in post-menopausal diabetic patients
The blood of patients was tested on weekly basis for different biochemical analysis such as liver tests, blood proteins in order to assess the toxicity of flaxseed lignan and β glucan
Summary
Diabetes mellitus is an endocrine disorder described by hyperglycemia and inadequate discharge of endogenous insulin. The beta islets cells of the pancreas produce insulin hormone (Pan et al 2017; American Diabetes Association 2019). Hyperglycemia is notably a serious and alarming health concern of developed and underdeveloped world communities. Prevalence of diabetes mellitus has enormously increased in developing countries in Pakistan during last few decades. In adequacy or lack of control over hyperglycemia in diabetic patients promote micro- and macro-vascular complication. Effective management of diabetes absolutely includes blood glucose monitoring, nutrition, exercise and medication (Piemonte 2011; De Boer et al 2017)
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