Abstract

Shi Ming Li#, Feng Zeng#, Wei wei Han and Bin Liu* Author Affiliations College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, China #Contributed equally to this study Received: April 11, 2020 | Published: April 21, 2020 Corresponding author: Bin Liu College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, China DOI: 10.26717/BJSTR.2020.27.004460

Highlights

  • Diabetes Mellitus (DM) is a chronic endocrine and metabolic disease caused by genetic factors, immune disorders, microbial infections and their toxins, free radical toxins, mental factors, and other pathogenic factors that act on the body

  • The results shown in (Table 2) indicate that in the 0th day, the body weight of the normal control group was significantly higher than that of the other five hyperglycemia groups, which is consistent with the symptoms of diabetes

  • The Grifola frondosamycelium polysaccharide (GFP) from the mycelia of G. frondosa cultured by solid state fermentation has hypoglycemic property

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Summary

Introduction

Diabetes Mellitus (DM) is a chronic endocrine and metabolic disease caused by genetic factors, immune disorders, microbial infections and their toxins, free radical toxins, mental factors, and other pathogenic factors that act on the body. A series of metabolic disorders such as sugar, protein, fat, water, and electrolytes, are caused by loss of insulin function and insulin resistance. Once the diabetes is out of control, it can cause many complications which would result in failure of the kidneys, eyes, feet and other parts, these diseases can hardly be cured. Diabetes is an independent cause of coronary heart diseases, and complications of macro vascular disease are the main cause of death in patients with diabetes [1]. The main treatment of diabetes is taking oral hypoglycemic drugs. Most of them have inescapable side effects on the human body, such as liver damage, gastrointestinal reactions and lactic acidosis

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