Abstract
BackgroundInsulinoma associated with pregnancy is a very rare condition and can be difficult to diagnose. Here, we present an interesting case of insulinoma occurring during pregnancy with special attention paid to the use of a continuous glucose monitoring system to detect hypoglycemia.Case presentationA 36-year-old white woman in the second trimester of pregnancy presented with recurrent episodes of hypoglycemia associated with neuroglycopenic symptoms. The use of a continuous glucose monitoring system confirmed hypoglycemia. Serum insulin, C-peptide, and proinsulin values confirmed endogenous hyperinsulinism. A tumor mass was localized at the tail of her pancreas by endoscopic ultrasound and confirmed by magnetic resonance imaging. Surgery performed at 21 weeks of gestation by distal pancreatectomy confirmed the presence of a 15 mm diameter endocrine tumor at the tail of her pancreas and led to a cure.ConclusionsHypoglycemia during pregnancy could be due to insulinoma. Use of a continuous glucose monitoring system could help to detect hypoglycemia in these patients.
Highlights
Insulinoma associated with pregnancy is a very rare condition and can be difficult to diagnose
Hypoglycemia during pregnancy could be due to insulinoma
Case presentation A 36-year-old white woman, 73 kg, 1.64 m, body mass index (BMI) 27.1 kg/m2, gravida 1 in 17 weeks of gestation presented to our hospital for the first time for evaluation of recurrent episodes of hypoglycemia associated with neuroglycopenic symptoms
Summary
Insulinoma is the most common neuroendocrine tumor of the pancreas and causes hypoglycemia due to endogenous hyperinsulinism. Case presentation A 36-year-old white woman, 73 kg, 1.64 m, body mass index (BMI) 27.1 kg/m2, gravida 1 in 17 weeks of gestation presented to our hospital for the first time for evaluation of recurrent episodes of hypoglycemia associated with neuroglycopenic symptoms. She had no chronic illness or medical conditions and had not taken any medication prior to hospital admission. After surgical excision of the tumor, our patient had no more hypoglycemic attacks Her postoperative blood glucose levels were within the normal range.
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